Production of donor-derived sperm after spermatogonial stem cell transplantation in the dog
نویسندگان
چکیده
منابع مشابه
Functional sperm produced after spermatogonial stem cell transplantation into rhesus.
S permatogonial stem cell (SSC) transplantation is a promising technique to circumvent sterility in prepubertal boys undergoing gonadotoxic treatments. While the cryopreservation of spermatogonial stem cells is being introduced in clinical practices worldwide, a lot of unanswered questions remain regarding their eventual transplantation. In this paper autologous and allogeneic SSC transplantati...
متن کاملSarcoidosis in donor-derived tissues after haematopoietic stem cell transplantation.
A 64-year-old Japanese female was diagnosed to have adult Tcell leukaemia in December 2009. She had neither any past history nor a family history of sarcoidosis. She underwent HSCT (unrelated bone marrow transplantation) in May 2010, after receiving treatment with fludarabine, busulfan, and total body irradiation, from a human leukocyte antigen (HLA)matched male donor who had no history of sarc...
متن کاملOsteoporosis after stem cell transplantation
Background Stem cell transplantation has become as a novel treatment for end-stage kidney, lung, heart , liver diseases and several hematologic disorders. Improved survival of transplant recipients has raised awareness of post-transplant complications. One of these complications is transplant-related osteoporosis. Methods In this manuscript we review prevention methods for transplant-relat...
متن کاملAdvances in spermatogonial stem cell transplantation.
Spermatogonial stem cell transplantation was first reported by Ralph Brinster's laboratory in 1994. It has proven to be a technological breakthrough in the study of both stem cells and Sertoli cell-germ cell interactions. This technique can be used to transfer testicular stem cells successfully from one animal to another of the same species (referred to as syngeneic transplants) and sometimes t...
متن کاملSpermatogonial Stem Cell Niche and Spermatogonial Stem Cell Transplantation in Zebrafish
BACKGROUND Spermatogonial stem cells (SSCs) are the foundation of spermatogenesis, and reside within a specific microenvironment in the testes called "niche" which regulates stem cell properties, such as, self-renewal, pluripotency, quiescence and their ability to differentiate. METHODOLOGY/PRINCIPAL FINDINGS Here, we introduce zebrafish as a new model for the study of SSCs in vertebrates. Us...
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ژورنال
عنوان ژورنال: REPRODUCTION
سال: 2008
ISSN: 1470-1626,1741-7899
DOI: 10.1530/rep-08-0226